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The Phase 2 trial enrolled participants with obesity and evaluated multiple dose levels over 48 weeks: 1 mg dose: 8.7% average body weight reduction 4 mg dose (escalated from 2 mg): 17.1% average body weight reduction 8 mg dose (escalated from 2 mg): 22.8% average body weight reduction 12 mg dose (escalated from 2 mg): 24.2% average body weight reduction Placebo: 2.1% average body weight reduction Those Phase 2 numbers were striking enough

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J Chem Educ 92:803810 Flynn AB, Amellal DG (2016) Chemical information literacy: pKa values-where do students go wrong

Certain peptides used in weight management may help support lean muscle mass, energy balance and overall body composition